Showing posts with label Bactericidal formulations for use in veterinary medicine. Show all posts
Showing posts with label Bactericidal formulations for use in veterinary medicine. Show all posts

Tuesday, May 19, 2009

Bactericidal formulations for use in veterinary medicine

A method of treating livestock infected with, or protecting livestock against infection from, bacteria which comprises administering to such livestock an antibacterially effective amount of a quinolonecarboxylic acid or derivative of the formula ##STR1## in which A represents nitrogen or C--R4,

R4 represents hydrogen, fluorine, chlorine, nitro or methyl,

B represents ##STR2## and B also represents ##STR3## when R1 does not denote cyclopropyl, and R5 represents hydrogen, a branched or unbranched alkyl group which has 1 to 4 carbon atoms and which can optionally be substituted by a hydroxyl or methoxy group,

R6 represents hydrogen, methyl or phenyl,

R7 represents hydrogen or methyl,

R8 represents amino, alkyl- or dialkylamino having 1 or 2 carbon atoms in the alkyl group, aminomethyl, alkyl- or dialkylaminomethyl having 1 or 2 carbon atoms in the alkyl group,

R1 represents an alkyl radical having 1 to 3 carbon atoms, cyclopropyl, 2-fluoroethyl vinyl, methoxy, 4-fluorophenyl or methylamino,

R2 represents hydrogen, alkyl having 1 to 6 carbon atoms, and cyclohexyl, benzyl, 2-oxopropyl, phenacyl and ethoxycarbonylmethyl,

R3 represents hydrogen, methyl or ethyl, Z represents oxygen, nitrogen which is substituted by methyl or phenyl, and CH2 --,

or a pharmaceutically utilizable salt thereof.