METHOCEL* hypromellose, ETHOCEL* ethylcellulose, and POLYOX™ Water-Soluble Resins NF each offer a long history of success in pharmaceuticals. These polymers have been used for their outstanding controlled release and film-forming functionalities. And each has already shown the potential to be an effective major component of oral film dosage forms.
They can be formulated into either clear or opaque films of varying thickness for different dissolution rates and applications. METHOCEL and POLYOX excipients are water-soluble, while water-insoluble ETHOCEL excipients give you additional capabilities to manage water-sensitive ingredients, or those that require greater taste masking functionality.
General Properties of METHOCEL Premium Cellulose Ethers
- Excellent film former
- Easy to swallow
- Range of viscosities and properties
- Excellent barrier properties
- Soluble in cold water
- Insoluble in hot water
- Non-ionic
- Limited solubility in organic solvents
- Reversible thermal gelation
- Surface Active
- Non-toxic
- Low taste and odor
- Non animal-based
- Maintains viscosity without bacterial growth
- Acts as a thickener, emulsifier, lubricant, binder, and film former
- Premium grades approved for use in pharmaceutical applications; compliant with USP/NF, EP, JP and FCC monographs
General Properties of ETHOCEL Premium Ethylcellulose Products
- Insoluble in water
- Soluble in common solvents
- Produces strong, flexible films
- Strong binding ability
- Colorless, odorless and tasteless
- Stable during handling and shipping
- Films are coherent and free from flaws and cracks
- Premium grades approved for use in pharmaceutical applications; compliant with USP/NF, EP, JP and FCC monographs
General Properties of POLYOX Water-Soluble Resins NF
- Tasteless, colorless, non-ionic and non-caloric
- Extremely fast hydration
- Hydrophilic
- Quickly forms hydrogels
- Enables melt extrusion processing
- Complies with USP polyethylene oxide NF monograph, requirement of Food Chemicals Codex, International Codex Alimentarius, and U.S. National Formulary (NF)
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